This overview of depression reviews what depression is, how it is manifested, and what can be done to treat it. The underlying psychological causes for depression cannot treated by anti-depressants. Yet psychiatrists have become psycho-pharmacologists rather than therapists. Current literature now questions that antidepressants are any stronger than placebo. Big pharma sponsored research outcomes have become transparent and conflicts of interest are now clear. The cause of depression is debated between challenging life situations, neurotransmitter levels, and genetic factors. Alternative therapies are reviewed and the importance of somatic psychotherapy is defined and explained.