Gout is a disease where too much uric acid accumulates in the blood stream and gets deposited in joints, the kidneys, and in the urine. When uric acid accumulates in a joint is causes inflammation and pain. When it is in the urine it can form a kidney stone. And, when it gets into the kidney substance itself it can cause kidney failure. Gout can be genetic but also is caused by taking certain diuretics such as hydrochlorthiazide. Mainstream medicine uses drugs to reduce inflammation and colchicine is used most often. Allopurinol is a specific treatment for gout; the mechanism is explained.