The December issue of the journal Aging Cell reported that molecular changes causing cancer are related to our genes and are driven mainly by aging, but are also dictated by what we eat, how much we weigh, and levels of vitamin D, selenium, and folic acid. This study out of Newcastle University in the UK showed that aging had the biggest effect on molecular changes but that selenium and vitamin D3 reduced negative epigenetic changes and that high blood folate and obesitiy increased them through their effects on a process known as "methylation."