Inflammation as a cause of chronic diseases is described and defined. The roles of cytokines and brown fat are explained. A lifestyle that includes exercise, stress reduction, sleep, weight management, and a healthy diet is a powerful antidote. Cholesterol is a marker of inflammation, not the cause of it.
Addendum: This is an excellent review of what inflammation and the information on it is still excellent.
However, since this audio was made there's been additional research about brown and white fat that is very interesting. It appears that brown fat is used to produce heat primarily and when it is burned it results in weight loss. White fat, on the other hand, must be used metabolically and sets the stage for the metabolic syndrome when it is around the abdomen.