Probiotic Synergy™ & ® Probiotic Supreme

Probiotic Synergy™ & ®

Probiotic Supreme

THIS INFORMATION IS PROVIDED FOR THE USE OF PHYSICIANS AND OTHER LICENSED HEALTH CARE PRACTITIONERS ONLY. THIS INFORMATION IS INTENDED FOR PHYSICIANS AND OTHER LICENSED HEALTH CARE PROVIDERS TO USE AS A BASIS FOR DETERMINING WHETHER OR NOT TO RECOMMEND THESE PRODUCTS TO THEIR PATIENTS. THIS MEDICAL AND SCIENTIFIC INFORMATION IS NOT FOR USE BY CONSUMERS. THE DIETARY SUPPLEMENT PRODUCTS OFFERED BY DESIGNS FOR HEALTH ARE NOT INTENDED FOR USE BY CONSUMERS AS A MEANS TO CURE, TREAT, PREVENT, DIAGNOSE, OR MITIGATE ANY DISEASE OR OTHER MEDICAL CONDITION.

Probiotic Synergy™

Probiotic Synergy™ uses the most advanced patented delivery and shelf stability technology available to ensure maximum  potency and viability.   This is achieved using the latest techniques designed to protect fragile probiotic organisms from harsh stomach acid and deliver the highest number of live organisms to the intestinal tract.

Probiotics are naturally  occurring  friendly  bacteria that are an integral  part of a healthy digestive system. They exist primarily  in the small and large intestine, enhancing health in several key ways. They help by assisting with food and nutrient assimilation, inhibiting  harmful  bacteria and by stimu- lating the immune system. Proper probiotic supplementation replaces intestinal  tract organisms  lost to antibiotic use, disease, poor  diets, stress and other factors.

Common Problems with Probiotic Supplements

• Strain identification and count is very difficult - only  the best companies  have the proper technology

• Preventing strain crossover

• Strain integrity and stability

• Very unstable to stomach acid

• Poor handling  by manufacturer and supplier common

• Moisture entering  capsules negatively affects longevity  of probiotic  viability

Practitioners and savvy consumers alike  are becoming  increasingly  aware of the importance  of supplementing  with  probiotic  bacteria. However, there continues  to be confusion regarding the potency and efficacy of probiotic dietary supplements.

It's all about survival!

Probiotic organisms must survive three major barriers in order to be beneficial for human health. Our new Probiotic Synergy™ is formulated to survive these barri- ers:

„ Barrier  1: Survival during the manufacturing process

„ Barrier  2: Survival on the shelf

„ Barrier  3: Survival through stomach acid

How?

Health Medicine Essentials became aware of new, cutting edge technology that uses the most advanced patented delivery and shelf stability technology available to ensure maxi- mum potency and viability. This is achieved using the latest BIO-tract Probiospheres® tableting technology designed to protect fragile probiotic  organisms from harsh stomach acid and deliver the highest number of live organ-isms to the intestinal tract.

Why the Probiosphere?

The Probiosphere shape has been shown to ensure maximum protection against stomach acid, resulting in the optimal delivery of viable organisms.

The end result—higher potency, superior delivery, and minimal waste.  A highly efficient, cost effective way to introduce probiotics and enjoy their  benefits, which include:

• Immune defense at the intestinal  and systemic level

• Minimize the side effects of antibiotics

• Minimize  allergic responses

• Prevention/alleviation  of traveler's diarrhea

• Prevention/alleviation of diarrhea and constipation in infants, adults and elderly

• Inhibit growth  of pathogenic  organisms:  bacteria,  yeast, parasites

• Improve digestion of lactose

• Alleviate inflammatory bowel disease/ulcerative colitis

• Vitamin K synthesis

• Alleviate atopic dermatitis

Probiotic Supreme

Probiotic  Supreme uses the same BioTract  technology  as the Probiotic Synergy™ but delivers 15 billion  organisms per dose* in a caplet form.  To deliver  this dose, the caplet was a better choice  as the final  ProBiosphere was too large to be practical.  Where Probiotic  Synergy™  can be used as an everyday maintenance  product,  Probiotic  Supreme can be used where a more  aggressive therapeutic approach may be required. Such situations may include those coming off antibiotic  therapies, those with  colitis,  candidiasis,  dysbiosis and many  other  types of GI conditions.

As the products are meant to release over an extended time frame (10-12 hours),  effective dosing need only take place twice a day. This also ensures delivery throughout the entire gastrointestinal tract.

*viable organisms at time of manufacture

References

1.  Lin  CK, Tsai HC, Lin  PP, Tsen HY, Tsai CC. Lactobacillus acidophilus LAP5 able to inhibit  the Salmonella  choleraesuis invasion to the human  Caco-2 epithelial  cell. Anaerobe. 2008 Nov;14(5):251-5.  Epub 2008 Aug 22.

2.  Betsi GI, Papadavid E, Falagas ME. Probiotics  for the treatment  or prevention  of atopic dermatitis:  a review of the evidence from randomized con- trolled trials. Am J Clin Dermatol. 2008;9(2):93-103.

3.  Prescott SL, Wickens K, Westcott L, Jung W, Currie  H, Black PN, Stanley TV, Mitchell EA, Fitzharris  P, Siebers R, Wu L, Crane J; Probiotic Study Group.

Supplementation with Lactobacillus rhamnosus or Bifidobacterium lactis probiotics in pregnancy increases cord blood interferon-gamma  and breast milk  transforming growth factor-beta and immunoglobin A detection. Clin Exp Allergy. 2008 Oct;38(10):1606-14.  Epub 2008 Jul 2.

4.  Johnston BC, Supina  AL, Ospina M, Vohra S. Probiotics  for the prevention  of pediatric  antibiotic-associated  diarrhea.  Cochrane Database Syst Rev.

2007 Apr 18;(2):CD004827.

5.  Toki  S, Kagaya S, Shinohara M, Wakiguchi H, Matsumoto T, Takahata Y, Morimatsu F, Saito H, Matsumoto K. Lactobacillus rhamnosus GG and

Lactobacillus casei suppress Escherichia coli-induced  chemokine  expression in intestinal  epithelial  cells. Int  Arch Allergy Immunol. 2009;148(1):45-

58. Epub 2008 Aug 21.

6.  Amit-Romach E, Uni Z, Reifen R. Therapeutic potential of two probiotics in inflammatory  bowel  disease as observed in the trinitrobenzene sulfonic acid model of colitis. Dis Colon Rectum. 2008 Dec;51(12):1828-36. Epub 2008 Jul 17.