Patients with low risk prostate cancer under active surveillance may benefit from vitamin D3 supplementation at 4000 IU per day according to an article in the Journal of Endocrinology Metabolism. In patients with Gleason 6 prostate cancers, those treated with 4000 IU of vitamin D3 for one year, 55% had a decrease in Gleason findings or fewer positive biopsies, 11% were without change, and 34% were somewhat worse. The PSA scores did not change in these patients. Levels of vitamin D less than 20 ng/ml showed a strong correlation with increased risk for death. We know that vitamin D increases differentiation of cancer cells.
Besides treating Gleason 6 prostate cancers with vitamin D, there are other approaches that could be of value, such as an alkaline diet, use of modified citrus pectin, flax seed oil, lifestyle strategies, mushrooms, antioxidants, vitamin C and K. There are many articles supporting this approach such as one done by Dean Ornish, MD.