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  A study published in the August issue of the Proceedings of the National Academy of Sciences showed that diets high in methylglyoxal, which is produced by dry heat, caused mice to develop early insulin resistance and increased body fat over four generations. This did not happen in the control mice not fed methylglyoxal. The abdominal fat in these mice...

An article published in May of 2012 in Nature Medicine reported that a chemical (methylglyoxal) that is produced excessively in people with painful diabetic neuropathy, appears to attack and modify a protein in nerve endings that causes nerves to become hypersensitive to pain, heat and cold. This may lead to investigating ways to increase an enzyme, glyoxalase,...