Infection with H pylori provides reliable protection against allergy-induced asthma by impairing the production of dendritic cells and triggering the accumulation of regulatory T-cells. Researchers published in the Journal of Clinical Investigation that the dramatic increase in allergic diseases in industrialized countries is linked to the rapid disappearance of specific micro-organisms that populate the human intestinal tract.
Other factors predisposing to the development of asthma include air pollution, smoking, and the hygiene hypothesis, and the widespread use of antibiotics.