Hista Eze:  Natural Support for Environmental Allergies

HistaEze

Natural Support for Environmental Allergies

THIS INFORMATION IS PROVIDED FOR THE USE OF PHYSICIANS AND OTHER LICENSED HEALTH CARE PRACTITIONERS ONLY. THIS INFORMATION IS INTENDED FOR PHYSICIANS AND OTHER LICENSED HEALTH CARE PROVIDERS TO USE AS A BASIS FOR DETERMINING WHETHER OR NOT TO RECOMMEND THESE PRODUCTS TO THEIR PATIENTS. THIS MEDICAL AND SCIENTIFIC INFORMATION IS NOT FOR USE BY CONSUMERS. THE DIETARY SUPPLEMENT PRODUCTS OFFERED BY DESIGNS FOR HEALTH ARE NOT INTENDED FOR USE BY CONSUMERS AS A MEANS TO CURE, TREAT, PREVENT, DIAGNOSE, OR MITIGATE ANY DISEASE OR OTHER MEDICAL CONDITION.

HistaEzeTM is designed to help support and counteract some of the main symptoms and immune reactions associated with environmental allergies (commonly known as hay fever or allergic rhinitis).

Key ingredients in this comprehensive allergy support formula include:

Tinofend®

Tinofend® extract, derived from the plant Tinospora cordifolia, has been
used since the early 1900’s in Ayurvedic medicine for its immunomodulat-
ing action. Tinofend contains a proprietary complex of polysaccharides and
polyphenols, and has been clinically shown to regulate key immune media-
tors and stimulate the activity of macrophages. Oxidative stress reduces the
immune system's ability to react to allergens. The polyphenols found in
Tinofend act as potent antioxidants, reducing oxidative stress, and thereby
allowing the immune system to perform efficiently. Most allergy treatments
work by blocking histamine or leukotrienes, which are pro-inflammatory
compounds responsible for allergic symptoms. This symptomatic approach while initially helpful, does not fully address the underlying cause.

Tinofend addresses the cause of allergies by increasing the number of phagocytic white blood cells, including macrophages, which help consume and rid the body of allergens, and by reducing the number of eosinophils (cells that contain histamine). The macrophages use phagocytosis to collect antigens which they can present to helper T-cells, alerting the T-cells to the fact that there is a foreign invader in the body, in turn triggering the proper immune response. Tinospora cordifolia (TC) reduc- es allergy symptoms through a multitude of immune regulatory mechanisms, including the activation of macrophages that occurs through TLR6 signaling, NF- B translocation and cytokine production.

The efficacy of Tinospora cordifolia (TC) extract in patients with allergic rhinitis was assessed in a randomized double-blind placebo controlled trial1. Seventy-five patients were randomly given either TC or placebo for 8 weeks. They were clinically examined and Hb% (hemoglobin percentage), TLC (total lymphocyte count), DLC (differential lymphocyte count) and nasal smear were per- formed. At the end of the trial baseline investigations were repeated, drug decoded and results analyzed. With TC treatment 100% relief was reported from sneezing in 83% patients, in 69% from nasal discharge, in 61% from nasal obstruction and in 71% from nasal pruritus (itching). In the placebo group, there was no relief in 79% from sneezing, in 84.8% from nasal discharge, in 83% from nasal obstruction, and in 88% from nasal pruritus. After TC, eosinophil and neutrophil count decreased and goblet cells were absent in nasal smear.