Insulin potentiated therapy is defined and its applications discussed. Cancer cells depend on sugar to make energy, whereas normal cells rely on fat. Thus, when sugar is withheld by injection insulin into the body, cancer cell membranes open wide to take in as much sugar as possible. It is when cell membranes are wide open that low dose chemotherapy is added. The toxic chemo gets into the cancer cells in much greater quantities when their membrane pores are wide open, and healthy cells are protected because they continue to have small pores.