Chronic disease, degenerative or autoimmune disease we talk about repair deficiency and inflammation. We measure inflammatory factors to determine how much disease is present. If cholesterol is healthy and not oxidized it is good; we need it to make hormones, vitamin D, and cell membranes. We need to measure oxidized forms of cholesterol and other fats. It is critical to remove biochemical stresses and actively support wellness. It would be wonderful if the National Institutes of Health and the main forces of medicine would evolve and focus on prevention. Choose sustainability for sustained remissions.