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A study published in Annals of Surgery in April of 2012 showed that bile, not acid, is the cause for Barrett's esophagus and esophageal cancer. This finding is especially important because current drug therapies for GERD focus largely on acid control. Drugs that block acid production might actually make the risk for esophageal cancer higher. Research...

  Barrett's esophagus develops in people who have bile reflux into the stomach and lower end of the esophagus in the presence of a hiatal hernia. It causes "intestinalization" of the lower end of the esophagus, which is then prone to develop esophageal cancer. However, unless there is dysplasia of the Barrett's esophagus, the risk for...