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Over the past decade there has been a 10 fold increase of the number of retractions and only a 44% increase in journal articles. Some retractions are from errors but many are from misconduct. At the heart of the problem is an economic incentive that fuels a hypercompetitive environment that fosters misconduct, sensationalism, and attempting to publish in high...

Antidepressants in kids are poorly regulated by the FDA even though their safety and effectiveness is debatable. Forrest Labs was caught bribing pediatricians with grants, speaking engagements, dinners, etc. This is the rule rather than the exception. Profit is the bottom line that determines what Big Pharma will do to sell whatever they can.

Research has documented that 91% of randomized clinical trials that have a financial conflict of interest (FCOI) have a positive outcome compared to those that do not. The most common FCOIs include research grants, employment, honorariums, and share ownership. Of the more than 100 studies reviewed, FCOIs were present more than 50% of the time! This data confirms...