According to a presentation at the Heart Rhythm Society in May of 2013, higher levels of estrogen are associated with an increased risk for sudden cardiac death (SCD) in both men and women. Testosterone on the other hand was lower in men and slightly higher in women with SCD. More than 350,000 people die annually in the US from SCD.
Some of the reason for higher levels of estrogen than expected, especially in postmenopausal women who are supposed to have low estrogen levels, is that our bodies convert chemicals from pesticides, plastics, and petroleum into powerful estrogen compounds called xeno-estrogens. They are very potent and likely explain why estrogen levels are higher than would normally be expected.