Even a few NSAIDs may be unsafe if you have heart disease. Shockingly data on 83,000 patients shows that even a week of treatment led to another heart attack or dying 45% more often if they had a prior heart attack. The percentage rose to 60% if treatment was for 30 days. There is no safe window for NSAIDs in people with a prior heart attack. There is also no safety for second generation NSAIDs called COX 2 inhibitors. Both Vioxx and Bextra have been removed from the market but Celebrex remains for reasons that are very questionable.