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Adding Proton Pump Inhibitors to NSAIDs
submitted by: admin on 11/22/2019
NSAIDs cause ulcers and proton pump inhibitors help prevent them. Why not combine them? Novel thought, but how wise is this? A clinical trial was done over a 30 day period that showed that GI bleeding was substantially reduced by this combination.
There are many problems with this kind of reasoning. First, most people aren't on NSAIDs for only 30 days...
Americans Get Too Many Colonoscopies
submitted by: admin on 05/12/2015
Gastroenterologists and the American Society for Gastroenterology recommend screening colonoscopies begin at age 50 and be repeated every 10 years unless there is a special indication for more often. However, the United States Preventive Services Task Force (USPSTF) is questioning this recommendation.
A study published in the September 2014 issue of...
Antidepressants Increase Adverse Reactions in Surgical Patients
submitted by: admin on 11/24/2019
According to an article published in the April 2013 issue of the journal Internal Medicine, patients on SSRI antidepressants at the time of surgery have a 20% increased mortality, 9% increased risk for bleeding, and 22% increased risk for readmission within a month of discharge from the hospital! This was based on a review of 530,000 surgical patients from...
Are Colonoscopies Effective?
submitted by: admin on 05/16/2015
Most of us assume the colonoscopy is a routine screening test we all need at age 50. However, the data is controversial and it can be argued that for people who are asymptomatic that there's no benefit when complications are considered.
Aspirin and Proton Pump Inhibitor Combinations
submitted by: admin on 10/26/2015
When you cannot tolerate aspirin should you just add one of the "purple pills?" The dangers of proton pump inhibitors are described.
Aspirin Cuts Cancer Risk
submitted by: admin on 10/26/2015
Aspirin has been found to protect against colon cancer and many other solid cancers. However, aspirin also causes GI bleeding in almost everyone over the long haul. A better way to prevent cancer is to clean up our toxic environment and live a healthy lifestyle. Direct to consumer ads give the wrong idea; they give you the idea that it is okay to live...
Aspirin Cuts Heart Attacks But Not Deaths or Strokes
submitted by: admin on 10/26/2015
Low dose aspirin can lower the risk of heart attacks in people without a history of heart disease by about 20%, but it does not lower the death rate or the risk of stroke. Also, there is the added risk of GI bleeding secondary to aspirin use. The risk for getting a heart attack in primary prevention is lowered from 2.3% to 1.8%, which comes to a 20% lower risk...
Aspirin for MI: Is it the Best Choice?
submitted by: admin on 10/26/2015
Side effects of aspirin outweigh the benefits for preventing heart attacks and strokes. GI bleeds are the major serious complications, but hemorrhagic stroke and retinal bleeds are also associated problems. It also causes leaky gut syndrome.
There are natural alternatives for aspirin that include fish oil, nattokinase, lumbrokinase, digestive enzymes that...
Aspirin, Tylenol, and NSAIDs Increase Blood Pressure
submitted by: admin on 09/18/2013
These over the counter analgesics increase the risk for hypertension in 20-50%. Fluid retention is one mechanism. DTC ads lead to their overuse. There are many other side effects as well.
Baby Aspirin: How Safe Is It?
submitted by: admin on 09/19/2013
When we think of aspirin, especially a baby aspirin, it seems innocuous. However, complications occur very commonly and can be devastating. Alternate solutions should be considered and they are discussed.
Chondroitin Plus Glucosamine are Equal to Celebrex
submitted by: admin on 05/26/2016
We all have pain from time to time and we want relief as soon as possible. The problem is that relieving pain with pharmaceutical drugs has side effects that are not minor, especially in the case of NSAIDs such as Advil, Aleve, Motrin, and Celebrex. There are about 30,000 deaths annually in the US from NSAIDs and more than 300,000 admissions to hospitals...
Colon Cancer Screening
submitted by: admin on 02/17/2015
Screening for colon cancer is controversial even though we are advised to have a colonoscopy at age 50 as a routine. However, in asymptomatic people the risk of perforation or GI bleeding offsets the benefits. The role of other screens such as occult blood in the stool, barium enemas, sigmoidoscopy and virtual colonoscopies is discussed.
Colonoscopy Screening Questioned
submitted by: admin on 06/18/2016
The Journal of the National Cancer Institute published an article saying that colonoscopy for primary screening might be going too far. I agree! The benefits, harms, and costs have not been determined. Checking the stool for ocult blood and flexible sigmoidoscopy have been shown to be of value but there's no data showing that colonoscopy gives additional...
Colonoscopy: Do You Need One?
submitted by: admin on 09/19/2013
Dr. Len discusses the pros and cons for a routine colonoscopy for colon cancer screening. In asymptomatic people without a family history of cancer, the risks of doing a colonoscopy may exceed the benefits. Bowel perforations and severe GI bleeding are complications in 1 in 200 tests. Other screening tests are reviewed too.
Do Familial Precancerous Polyps Predict Colon Cancer?
submitted by: admin on 06/18/2016
When do you need a colonoscopy? An article in Annals of Internal Medicine in May of 2012 stated that there's insufficient evidence to recommend earlier or more frequent colonoscopies for people who have a first degree relative with a precancerous polyp unless the polyp is advanced. About 30-50% of people have polyps that are precancerous, but only 5-10% warrant...
Do We Do Too Many Angioplasties and Stents?
submitted by: admin on 09/20/2013
Most angioplasties and stents used to treat acute heart attacks or unstable angina in the US are necessary and lifesaving. We know that these procedures are not indicated for people with coronary artery blockages who are stable; only about 3% benefit from these invasive procedures compared to medical treatment alone using pharmaceutical drugs. There is also a...
Fever Reducing Medications Increase Mortality From Influenza
submitted by: admin on 10/22/2018
A study from McMaster University published in the March issue of the Proceedings of the Royal Society B showed that fever-reducing drugs that include aspirin, Tylenol, and NSAIDs such as ibuprofen, could lead to thousands of more cases of influenza and more deaths because of it. They pointed out that ill people may give off more virus when fever is reduced....
H. Pylori DNA Reduces Inflammation from Colitis
submitted by: admin on 09/22/2013
DNA from H. pylori minimizes the effects of colitis in mice with regard to weight loss, GI bleeding, and stool consistency. More than 50% of the world has significant amounts of this microbe in their intestinal tracts. The bug in some settings could be good for us! Radical treatment with triple therapy that includes several antibiotics, acid blockers,...
Hiatal Hernias: How to Manage Them
submitted by: admin on 09/24/2013
Hiatal hernias and their complications are defined and treatments offered. The physiology and the complications of treatment are reviewed.
How Do You Know if the Treatment Your Doctor Prescribes is Good for You?
submitted by: admin on 03/05/2015
How Do You Know if the Treatment Your Doctor Prescribes is Good for You?
According to an article published in the NY Times on February 2, 2015, far fewer people benefit from medical treatment than we're led to believe from our doctors, advertisements such as direct to consumer TV ads, ads in medical journals, and even in medical journal articles, and...
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